Jan 21, 2026 · 32 min
In this conversation, Alex Larson chats with Jeff Stout to discuss the significance of buffering supplements, particularly beta-alanine and sodium bicarbonate, in enhancing athletic performance. He explains how these supplements work to improve muscle buffering capacity, delay fatigue, and potentially enhance endurance and power in athletes. The discussion also covers the proper dosages, timing, and the importance of combining both supplements for optimal results. 00:00 Introduction to Buffering Supplements 02:03 The Role of Beta-Alanine in Muscle Buffering 04:39 Understanding Dosage and Timing for Beta-Alanine 06:33 Side Effects of Beta-Alanine: Paresthesia Explained 11:14 Evaluating the Need for Beta-Alanine in Endurance Sports 14:02 Sodium Bicarbonate: Mechanism and Benefits 15:56 Sodium Bicarbonate in Endurance Events 17:51 Modes of Sodium Bicarbonate Supplementation 29:44 Combining Beta-Alanine and Sodium Bicarbonate This episode is brought to you by Thorne. Shop Thorne Supplements and get 15% off Resources Mentioned in This Episode: Apply for 1:1 Coaching with an ALN Dietitian https://alexlarsonnutrition.com Connect with Me: Instagram: @alexlarsonnutrition Website: alexlarsonnutrition.com Don’t Forget to Subscribe! Click that follow button to stay updated on future episodes packed with actionable insights and expert advice for endurance athletes. Have Questions or Suggestions? Send me a message, and I might cover it in a future episode!